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On 25 March 2024, the Health and Safety Executive (HSE) notified to the World Trade Organisation (WTO) the proposed amendments to the GB Mandatory Classification List (MCL), which will introduced new mandatory classifications under the GB Classification, Labelling and Packaging (CLP) Regulation for a number of substances. For all information on GB CLP, please see the relevant Reference Zone page.
Below is a list of substances which have an INCI name and may therefore be used as cosmetic ingredients that have a proposed Carcinogen, Mutagen or toxic for Reprotoxic (CMR) classification. Only the CMR mandatory classification as a would trigger the Article 15 of the UK Cosmetics Regulation (UKCR), where the ingredient would need to be banned or restricted for use. For more information on CMR substances, please see the relevant Reference Zone page.
- Trimethylbenzoyl diphenylphosphine oxide (CAS 75980-60-8): CMR 1B reprotox. This ingredient is therefore expected to be banned for use in cosmetics and added to Annex II of the UK Cosmetics Regulation.
- Hexyl salicylate (CAS 6259-76-3): CMR 2reprotox. This ingredient is being defended by the cosmetics industry and, if defence is successful, it may be added to Annex III of the UK Cosmetics Regulation.
The WTO notification is open for comments for 60 days from the date of notification. Once the legislation is officially published and entered into force (expected for Q3 2024), the application date for mandatory classifications is scheduled for Q4 2026.
