Published: 29 November 2023  (Updated: 12 January 2024)

IMPORTANT – Hexamethylindanopyran Usage Check

The European Chemicals Agency (ECHA) has listed a new entry within its Registry of Intentions with proposed Carcinogenic, Mutagenic and Reprotoxic (CMR) classifications.  According to Article 15 of the UK and EU Cosmetics Regulations, if a cosmetic ingredient receives a CMR classification, specific safety information must be submitted to, and reviewed by, the authorities to allow the ingredient to continue being used.  The objective of this ingredient defence is to secure an Annex III entry for Hexamethylindanopyran within the Cosmetics Regulation if it receives the below-proposed CMR classification.

HEXAMETHYLINDANOPYRAN (HHCB, Galaxolide, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran (EC 214-946-9 , CAS 1222-05-5).

  • Fragrance
  • Proposed CMR reprotox (no category yet), ED Human Health (no category yet) –France
  • Expected submission date 28 February 2024

Companies who are interested in contributing to the defence work for Hexamethylindanopyran, please contact CTPA at [email protected] by 13 December 2023.

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