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The International Collaboration on Cosmetic Safety (ICCS) published their Best Practice Guidance on read across, providing insights into using a read-across approach for both human health and environmental safety.
This BPG explains the key principles and steps involved in read-across based on the analogue and category approach, namely problem formulation, analogue(s) identification and evaluation, suitability assessment and characterization and mitigation of potential uncertainties related to the chosen analogue(s). The importance of documentation and transparency is emphasised, with guidance on reporting decisions, input variables and assumptions.
The document aims to increase the use and acceptance of read-across by proposing a structured workflow for safety assessors, in order to inform hazard and safety assessments for both human health and environment without the need for new animal testing.
