Find us on...
On 25 November 2025, the Health and Safety Executive (HSE) published guidance for registrants on meeting the toxicological and ecotoxicological information requirements laid out in Annexes VII-X of the UK Registration, Evaluation and Authorisation of Chemicals (REACH) Regulation. The guidance was developed in collaboration with the Environment Agency.
This guidance outlines ways in which new tests on animals might be avoided or minimised, as well as ways to implement the 3Rs (Reduction, Refinement and Replacement), in order to meet the requirement under Article 25 of UK REACH whereby animal testing must only be undertaken as a last resort.
Registrants should use this guidance when considering how to meet information requirements in the UK REACH annex(es) relevant to their registration tonnage band.
