Overview of the Cosmetic Product Safety Report (CPSR)1 hour 17 minutes

This module provides an overview of the Cosmetic Product Safety Report (CPSR) as detailed in Annex I of the UK and EU Cosmetics Regulations, as well as insights from Trading Standards (the UK enforcement authority) as to what they expect to see when inspecting a CPSR.

Key Toxicological Principles in Cosmetic Safety Assessment49 minutes

This module explains the basic principles of the safety assessment of cosmetics, such as hazard identification, exposure assessment and risk characterisation. It also explains the concept of Margin of Safety (MoS) and how to address data gaps by using approaches such as Threshold of Toxicological Concern (TTC), read-across and Weight of Evidence (WoE).

Local Toxicity1 hour 13 minutes

This module explains toxicological considerations and test methods to assess local toxicity endpoints including skin irritation, eye irritation, skin sensitisation and phototoxicity.

Systemic Toxicity53 minutes

This module explains the principles behind systemic toxicity and in vivo and in vitro test methods to assess repeated dose toxicity, reproductive toxicity, and carcinogenicity/ mutagenicity/genotoxicity.

Stability, Microbiology, Packaging and Cosmetovigilance1 hour 1 minutes

This module explains the impact of product stability, microbiological quality, packaging and cosmetovigilance data on the safety assessment of cosmetics.

Fragrance Compounds, Botanical Ingredients and Nanomaterials1 hour 13 minutes

This module explains the key considerations and approaches to assess the safety of fragrance compounds, botanical ingredients and nanomaterials.

Next Generation Risk Assessment (NGRA) for Cosmetic Safety Assessment44 minutes

This module explains the Next Generation Risk Assessment (NGRA) for the safety assessment of cosmetics, which is a hypothesis led, non-animal approach to safety assessment using human relevant in vitro assays and computational tools to aid decision making. The module explores the key concepts of NGRA, some of the tools or New Approach Methodologies (NAMs) and how the outputs can be brought together to make decisions on cosmetic safety.

Environmental Safety Assessment for Cosmetics1 hour 13 minutes

This module introduces environmental safety assessment, from the basic principles to the key concepts for hazard and exposure assessment and risk characterisation.